This notice solicits applications for the Thalassemia Program. The purpose of this program is to improve quality of care delivered to individuals with clinically significant thalassemia, especially those who are transfusion-dependent. Awardees will establish collaborative regional networks that use collective impact[1] strategies and telehealth to (1) promote the use of expert recommended and evidence-informed care, and (2) improve capacity of primary and subspecialty care clinicians to manage thalassemia, particularly in remote and/or medically underserved communities. [1] Bonzon E, Callahan T. (2012 Nov/Dec). Systems-Level Impact: Using the Collective Impact Framework for Public Health Systems Building. Retrieved from: http://www.amchp.org/AboutAMCHP/Newsletters/Pulse/Archive/2012/NovDec2012/Pages/Feature5.aspx