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Quality Improvement Solutions for Sustained Epidemic Control Project (QISSEC)

  • Program Name:Quality Improvement Capacity for Impact Project
  • Activity Code:U1N
  • Application Available:3/8/2021
  • Application Deadline:5/7/2021
  • Created By:Wildberger, William
  • Created On:10/6/2020
  • Last Updated by:Wildberger, William
  • Last Updated On:3/8/2021
  • Estimated Project Start Date:9/30/2021

 Details of the changes posted in this announcement

Not Available

 Announcement Information

Announcement Number HRSA-21-096
Announcement Code
CFDA Number 93.266
Provisional No
Activity Code U1N
Competitive Yes
Fiscal Year 2021


This notice announces the opportunity to apply for funding for the Quality Improvement Solutions for Sustained Epidemic Control Project (QISSEC). The purpose of this project is to facilitate improvements in quality across the HIV care continuum at the site level (defined as the location where persons diagnosed with HIV receive care and treatment) and within the community. The project attempts to improve the effectiveness, efficiency, patient-centeredness, safety, accessibility, and equity of the HIV services in low to middle-income countries (LMIC) as identified by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) program. FY21 PEPFAR priorities recognize quality health services as essential in order to ensure that optimal health outcomes are met on a daily and routine basis. Therefore, all PEPFAR country programs must incorporate explicit quality management (QM) practices, including both quality assurance (QA) and quality improvement (QI) activities into service delivery and partner management. Focused on building the capacity of countries to sustain and spread QI methodologies, improve documentation of efforts, and continuously enhance staff knowledge, QISSEC strives to impact the delivery of quality HIV services, improve health outcomes, and support HIV/AIDS epidemic control. This Notice of Funding Opportunity (NOFO) will fund two cooperative agreements in support of the PEPFAR focus on the management of evidence-informed interventions for scale-up and spread. The successful applicants will facilitate solutions for long-term change management approaches and sustainability of QA and QI activity. The QISSEC shall focus on developing innovative strategies to improve the delivery of HIV quality care and treatment for use by facilities that serve the most vulnerable individuals in PEPFAR-supported LMICs. Using quality improvement methodologies, tools, and techniques, the project will identify gaps in service delivery, and develop culturally and medically appropriate, sustainable interventions targeted to PEPFAR- identified vulnerable and key populations. Over 18 years PEPFAR has evolved to a complex and high impact program, with mature stakeholders and partners showing that epidemic control is indeed possible. It is in this context that HRSA is renewing its commitment to PEPFAR and specifically seeking to fill gaps as well as to bring targeted and innovative solutions to the remaining barriers to epidemic control around the globe. The PEPFAR 2021 Country Operational Plan Guidance for all PEPFAR Countries ( suggests all PEPFAR country programs must incorporate explicit quality management practices, including both QA and QI activities, into service delivery and partner management.

 Legislative Information

Public Law 108-25 (the United States Leadership Against HIV/AIDS, Tuberculosis and Malaria Act of 2003) [22 U.S.C. 7601 et seq.], Public Law 110-293 (the Tom Lantos and Henry Hyde United States Leadership Against HIV/AIDS, Tuberculosis, and Malaria R

 Application Information

Application Available 03/08/2021
Application Deadline 05/07/2021
Supplemental Application Deadline N/A
Explanation for Deadline N/A
Archive Date 07/06/2021
Letter of Intent Not required
Application Package SF424
Allow Applications to be Reopened in EHBs No
FOA Available Yes
Competitive Application Types Supported New
Allow Electronic Submission N/A
Page Limit for Application
Allow Multiple Applications
from an Organization from
Electronic Submission Instruction Electronic submission is/will be available in Grants.Gov

 General Information

Projected Award Date N/A
Estimated Project Period N/A
Estimated Project Start Date 09/30/2021
Estimated Project End Date 09/29/2026
Estimated Amount of this Competition $20,000,000.00
Estimated Number of Awards 2
Estimated Average Size of Awards $0.00
Cost Sharing No
Cooperative Agreement Yes

 Contact Information

Name Tracey Gantt, MSN, RN, PHNA-BC
Phone Number 301-443-1219

 Download Information

Expand FOA (Guidance) Attachment (Maximum 1)
Document Name Size Date Attached Description
OGH HRSA_21_096 U1N QISSEC final to post.pdf 459 kB 03/08/2021
Expand Application Package (Maximum 1)
No documents attached
Expand User Guide (Maximum 1)
No documents attached

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