This notice announces the opportunity to apply for funding under the Supporting Fetal Alcohol Spectrum Disorders Screening and Intervention program. This program has two related purposes: to reduce alcohol use among pregnant women, and to improve developmental outcomes for children and adolescents with a suspected or diagnosed Fetal Alcohol Spectrum Disorder (FASD), in states, U.S. territories, tribes/tribal organizations, or communities that have high rates of binge drinking among pregnant women, especially in rural areas. Specifically, the goals of this program are: 1) to improve the ability of primary care providers (PCPs) serving pregnant women, to screen their patient population for alcohol use, provide brief intervention, and refer high-risk pregnant women to specialty care; and, 2) to improve the ability of PCPs serving children and adolescents to screen their patient population for prenatal alcohol exposure among those suspected of FASD, and manage and provide referrals to necessary services for those identified with FASD.2 PCPs may include, but are not limited to, maternity care, family medicine, pediatric and nursing providers, especially those practicing in rural areas3 and medically underserved communities.4 The recipient will use a variety of evidence-based modalities including telehealth approaches, to increase PCP knowledge and provide technical assistance (TA) to implement and sustain practice change among PCPs.