This notice announces the opportunity to apply for funding under the Regional Pediatric Pandemic Network program. The purpose of this program is to coordinate among the Nation’s children’s hospitals and their communities in preparing for and responding to global health threats, including the coordination, preparation, response, and real-time dissemination of research-informed pediatric care for future pandemics.1 The Regional Pediatric Pandemic Network (the “Network”) will be comprised of five children’s hospitals or their affiliated university pediatric partners in geographically diverse areas across the United States that will work collaboratively across institutions to plan and implement the work of this cooperative agreement. The Network will coordinate the Nation's children’s hospitals and other pediatric experts to strengthen partnerships with existing local, state, regional, and national emergency preparedness systems to ensure the needs of all children are addressed within preparedness and response activities. This program will fund one award. You must submit a proposal to support a network of five identified children’s hospitals or their affiliated university pediatric partners that collectively meet the criteria described in the Section III: Eligibility. The primary recipient (center that is listed as the grantee of record on the Notice of Award) is one of the five Children’s hospitals or their affiliated university partners.